Install rossetta

Rosetta works automatically in the background whenever you use an app built only for Mac computers with an Intel processor. It translates the app for use with Apple silicon.

In most cases, you won't notice any difference in the performance of an app that needs Rosetta. But you should contact the app developer to enquire about a version that can use the full power and performance of Apple silicon natively.

For universal apps only, the Info window includes the setting "Open using Rosetta". As you noticed, the command you ran had a "mode" option and that you mentioned "bin" specifically. There are several other flags and modes that you can use to build certain parts or features. NOTE when you build with different extras, the extension will change. If you are interested in working with Rosetta code, you can build Rosetta using the Rosetta Xcode project.

You can use it to build, run, debug, browse, and edit the source code. You can find the instructions on how to use Xcode to build Rosetta here. PyRosetta is an interactive Python-based interface to Rosetta, allowing users to create custom molecular modeling algorithms with Rosetta sampling and scoring functions using Python scripting.

PyRosetta was written for Python 2. You can follow instructions to download and install PyRosetta here and here. For Macs, install the XCode development packages.

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You can use the following command to specify the proxy server replacing it with YOUR proxy server. Rosetta is used by a number of modules in Phenix phenix.